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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
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pubmed:dateCreated |
1982-12-16
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pubmed:abstractText |
3-Deazaguanine (3-DG) is a new purine antagonist that is active against slow- and rapid-growing solid experimental tumors, especially those that are models for human breast carcinomas. These tumors include mammary adenocarcinomas 13762, R3230AC, and C3H/16C. 3-DG also showed positive activity against leukemias L1210 and L1210/araC, adenocarcinoma 755, and EMT-6 mammary adenocarcinoma. On the basis of its activity against these tumors, 3-DG is to undergo clinical trials.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0361-5960
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
66
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1853-8
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:7127323-Adenocarcinoma,
pubmed-meshheading:7127323-Animals,
pubmed-meshheading:7127323-Antimetabolites,
pubmed-meshheading:7127323-Breast Neoplasms,
pubmed-meshheading:7127323-Cell Line,
pubmed-meshheading:7127323-Female,
pubmed-meshheading:7127323-Guanine,
pubmed-meshheading:7127323-Leukemia, Experimental,
pubmed-meshheading:7127323-Mice,
pubmed-meshheading:7127323-Neoplasm Transplantation,
pubmed-meshheading:7127323-Rats
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pubmed:year |
1982
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pubmed:articleTitle |
3-deazaguanine, a candidate drug for the chemotherapy of breast carcinomas?
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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