Linked Life Data

7124865

Source:http://linkedlifedata.com/resource/pubmed/id/7124865

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1982-12-3
pubmed:abstractText
The management of the pregnant patient with immune thrombocytopenia is complicated by the unavailability of the fetal platelet count. Since the transplacental passage of antiplatelet antibodies mediates infant thrombocytopenia, measurement of maternal platelet-associated IgG might predict infant outcome. We related the maternal platelet count and platelet-associated IgG level to the infant's platelet count in 41 pregnancies in 38 patients who were clinically diagnosed as having immune thrombocytopenia. Fifteen of 39 live-born infants were thrombocytopenic at delivery. Maternal platelet-associated IgG was predictive of infant platelet count but maternal platelet count was not; only one of the 20 infants delivered of the 18 thrombocytopenic mothers with normal platelet-associated IgG was affected, whereas 11 of 12 thrombocytopenic mothers with elevated platelet-associated IgG had thrombocytopenic infants. Five infants died in utero between 18 and 28 weeks' gestation, but otherwise there was no significant morbidity in the live births. Measurement of platelet associated IgG in mothers with immune thrombocytopenia during pregnancy can be used to predict infant thrombocytopenia, although it does not predict the severity of the thrombocytopenia.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0002-9378
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
144
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
449-54
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
The prenatal prediction of thrombocytopenia in infants of mothers with clinically diagnosed immune thrombocytopenia.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't