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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1982-12-2
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pubmed:abstractText |
Among 37 patients treated with amiodarone, an antiarrhythmic drug, a typical keratopathy developed in 35, none of whom had ocular complaints. The keratopathy resembled that seen with Fabry's disease and chloroquine use, as did the membrane-bound lamellar bodies detected by electron microscopy in all layers of the corneal epithelium in the one patient with marked keratopathy in whom a corneal biopsy was performed; membrane-bound bodies, mostly granular, were also noted within this patient's stromal keratocytes. The possible pathogenesis of the keratopathy as a type of drug-induced lipidosis is discussed.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0008-4182
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
17
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
96-9
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pubmed:dateRevised |
2010-9-8
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pubmed:meshHeading |
pubmed-meshheading:7116220-Adult,
pubmed-meshheading:7116220-Aged,
pubmed-meshheading:7116220-Amiodarone,
pubmed-meshheading:7116220-Benzofurans,
pubmed-meshheading:7116220-Cornea,
pubmed-meshheading:7116220-Corneal Diseases,
pubmed-meshheading:7116220-Humans,
pubmed-meshheading:7116220-Lipidoses,
pubmed-meshheading:7116220-Microscopy, Electron,
pubmed-meshheading:7116220-Middle Aged
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pubmed:year |
1982
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pubmed:articleTitle |
Amiodarone-induced cornea verticillata.
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pubmed:publicationType |
Journal Article
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