Linked Life Data

7115559

Source:http://linkedlifedata.com/resource/pubmed/id/7115559

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1982-9-10
pubmed:abstractText
A patient with systemic lupus erythematosus and severe thrombocytopenia was refractory to therapy with prednisone, alone or in combination with cyclophosphamide or vincristine. Intravenous pulse therapy with methylprednisolone was associated with an increased platelet count from 4,000/mm3, to 52,000/mm3, but the response was short-lived. A second course of pulse therapy was also successful, and splenectomy was safely performed. The platelet count has remained normal for 15 months after surgery, allowing prednisone to be tapered and discontinued. Intravenous pulse therapy with methylprednisolone may be a safe alternative in preparing patients with profound, refractory thrombocytopenia for splenectomy.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0315-162X
pubmed:author
pubmed:issnType
Print
pubmed:volume
9
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
311-4
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:articleTitle
Pulse corticosteroid therapy for refractory thrombocytopenia in systemic lupus erythematosus.
pubmed:publicationType
Journal Article, Case Reports