Linked Life Data

7111345

Source:http://linkedlifedata.com/resource/pubmed/id/7111345

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1982-10-12
pubmed:abstractText
Previous studies have found that naloxone and other opiate antagonists will decrease the food and water intake of experimental animals. The present study investigated the possibility that these effects may be due to a generalized action of opiate antagonists to block an endogenous reward system. A direct comparison was made between the effects of naloxone and naltrexone on FR responding maintained by small quantities of milk and on the consumption of milk when it was freely available. Both drugs reduced milk consumption at all doses (0.3-30 mg/kg) but produced only small decreases in FR response rates at the highest doses. These results do not support the view that the actions of opiate antagonists on eating and drinking represent an inhibitory action on central reward mechanisms.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0091-3057
pubmed:author
pubmed:issnType
Print
pubmed:volume
16
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1013-5
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
A comparison of the effects of opiate antagonists on operant and ingestive behavior.
pubmed:publicationType
Journal Article