Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
1982-8-7
pubmed:abstractText
(1) The induction of vitellogenin synthesis in chicken liver by an estrogen implant as well as the decline of vitellogenin synthesis and nuclear receptor concentration after withdrawal of the implant were studied. For the detection of vitellogenin the SAC immunoprecipitation technique was used. The nuclear receptor decreases very rapidly and somewhat earlier than the capacity of the liver to synthesize vitellogenin. (2) The inhibition by antiestrogens of the estrogen-induced vitellogenin synthesis as well as of the accumulation of the estrogen-receptor complex in the nucleus was investigated. Tamoxifen as well as the recently described 1,1,2,2-tetramethyl-1,2-bis(4'-hydroxyphenyl)ethane were found to be true antiestrogens in the chicken liver, i.e. they inhibit estrogen-induced vitellogenin synthesis but themselves cause no induction.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0303-7207
pubmed:author
pubmed:issnType
Print
pubmed:volume
26
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
231-42
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
The estrogen-induced vitellogenin synthesis in chicken liver after estrogen withdrawal or antiestrogen treatment.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't