Linked Life Data

7081121

Source:http://linkedlifedata.com/resource/pubmed/id/7081121

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1982-7-22
pubmed:abstractText
The influence of ascorbic acid intake on vitamin B6 metabolism in humans was determined in three separate studies. Five subjects in study I and two subjects in study II received 0.5 ( 2 days) and 1 g (7 days) doses of L-ascorbic acid (AA), respectively, before supplementation with 2 mg of pyridoxine hydrochloride (PN-HCl). From daily diet records the percentage of the intake of vitamin B6 excreted as urinary 4-pyridoxic acid (4PA) was calculated. Because of the variability in vitamin B6 intake, study III was conducted with four male and four female subjects, who received identical meals on days 2, 3, 9, and 10 and 1 g of AA on days 4 to 10. Two milligrams of PN.HCl were given the day before and the last day of AA administration. In contrast to studies I and II, where excretion of 4PA appeared to increase on the day of PN.HCl supplementation plus AA compared to pre-AA, urinary 4PA excretion in the eight subjects of study III was not significantly different when the same PN.HCl supplemented pre-AA and post-AA days were compared. Also, the fasting plasma pyridoxal 5'-phosphate level was not significantly altered when AA was administered. It is concluded that short-term AA supplementation did not alter vitamin B6 metabolism.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0002-9165
pubmed:author
pubmed:issnType
Print
pubmed:volume
35
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1400-7
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Effect of high dose ascorbic acid on vitamin B6 metabolism.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't