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rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
3
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pubmed:dateCreated |
1978-12-27
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|
pubmed:abstractText |
The ability of aluminium phosphate and calcium phosphate to stimulate the synthesis of tetanus toxoid-specific anaphilactic and antitoxic antibodies is compared. The observed differences in the kinetics of IgG1a, IgG1b and antitoxines are quantitative--titres after application of aluminium phosphate are higher. Booster immunization with aluminium but not calcium phosphate-adsorbed toxoid leads to a prolonged synthesis of specific IgE. It is hypothesized that the regular application of aluminium compound-containing vaccines on the entire population could be one of the factors leading to the observed increase of allergic diseases.
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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|
pubmed:month |
Jun
|
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pubmed:issn |
0105-4538
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|
pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
33
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
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pubmed:pagination |
155-9
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|
pubmed:dateRevised |
2003-11-14
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|
pubmed:meshHeading |
pubmed-meshheading:707792-Aluminum,
pubmed-meshheading:707792-Anaphylaxis,
pubmed-meshheading:707792-Animals,
pubmed-meshheading:707792-Antibody Formation,
pubmed-meshheading:707792-Antibody Specificity,
pubmed-meshheading:707792-Calcium Phosphates,
pubmed-meshheading:707792-Guinea Pigs,
pubmed-meshheading:707792-Immunoglobulin E,
pubmed-meshheading:707792-Immunoglobulin G,
pubmed-meshheading:707792-Kinetics,
pubmed-meshheading:707792-Male,
pubmed-meshheading:707792-Phosphates,
pubmed-meshheading:707792-Tetanus Toxoid
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|
pubmed:year |
1978
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|
pubmed:articleTitle |
Aluminium phosphate but not calcium phosphate stimulates the specific IgE response in guinea pigs to tetanus toxoid.
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pubmed:publicationType |
Journal Article
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