Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1 Pt 1
pubmed:dateCreated
1982-6-24
pubmed:abstractText
The comparative anatomy of the normal eustachian tube (ET) and normal middle ear cavity of three animal species (rat, gerbil, and chinchilla) is described relating to the usefulness of these animals as models for otitis media (OM). Routine histological and anatomical techniques and procedures were used. The gerbil and chinchilla, although of different sizes, are quite similar, having hypertrophied middle ear bullae, nearly vertical ET, and similar histology including seromucous glands draining directly into the ET. In contrast, the rat has a small bulla, a nearly horizontal ET, and a large concentration of goblet cells but few mucous glands in the ET. It appears that the chinchilla and the gerbil may serve as alternative models for OM research. Chinchillas and gerbils are relatively free of naturally occurring OM, while the rat has a high incidence of naturally occurring OM.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:issn
0003-4894
pubmed:author
pubmed:issnType
Print
pubmed:volume
91
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
82-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
Comparative anatomy of eustachian tube and middle ear cavity in animal models for otitis media.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't