Linked Life Data

7050280

Source:http://linkedlifedata.com/resource/pubmed/id/7050280

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1982-10-21
pubmed:abstractText
The effect of the dopamine antagonist, haloperidol, on arginine-vasopressin (AVP) release induced by angiotensin II was studied in six dehydrated conscious dogs. Angiotensin II (10 ng/kg per min) alone caused a twofold increase (P less than 0.05) in plasma AVP concentration, a 25 mmHg increase (P less than 0.01) in mean arterial blood pressure (ABP) and a 70% decrease (P less than 0.01) in plasma renin activity (PRA). In the presence of haloperidol (3 micrograms/kg per min), angiotensin II caused similar changes in mean ABP (25 mmHg; P less than 0.01) and PRA (-65%, P less than 0.01), but a small insignificant decrease in plasma AVP (-22%). The AVP response to angiotensin II in the presence of haloperidol was significantly (P less than 0.05) different from its response to angiotensin II alone. Neither haloperidol alone nor the two vehicles had any effect on plasma AVP or mean ABP but PRA dropped slightly. The results suggest that a dopaminergic mechanism may be involved in angiotensin II-induced AVP release.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0022-0795
pubmed:author
pubmed:issnType
Print
pubmed:volume
94
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
243-9
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Role of dopamine in the angiotensin II-induced vasopressin release in the conscious dehydrated dog.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't