Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1982-7-19
pubmed:abstractText
The analgesic efficacy and safety of intramuscular meptazinol and pethidine in the first stage of labour were compared in a randomized double-blind trial in 358 patients. Pain relief was measured on a verbal rating scale, maternal side effects were recorded and neonatal outcome assessed in the first 24 h. Pain relief during the first hour after injection was significantly greater in the meptazinol than in the pethidine group at 45 and 60 min. Thereafter, there was no difference between the treatments, and the duration of action was approximately the same. Twenty-eight per cent of patients experienced side effects after meptazinol compared with 35% after pethidine. The commonest were nausea and vomiting with a similar incidence in both groups. Most of the neonatal observations revealed no difference between the two drugs, but significantly more babies whose mothers had received meptazinol had an Apgar score of greater than or equal to 8 at 1 min after birth.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0306-5456
pubmed:author
pubmed:issnType
Print
pubmed:volume
89
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
318-22
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Double-blind comparison of meptazinol and pethidine in labour.
pubmed:publicationType
Journal Article, Clinical Trial, Comparative Study, Randomized Controlled Trial