Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1981-11-19
pubmed:abstractText
The coexistence of two types of plasminogen activators in human uterine fluid was demonstrated. Immunologically, one was urokinase-like and the other tissue activator-like. Both activators contributed to the fibrinolytic activity of uterine fluid. Urokinase-like immunoreactivity decreased from the proliferative phase to the luteal phase and increased premenstrually. The increase in fibrinolytic activity premenstrually was ascribed mainly to an increase in concentration of the urokinase-like plasminogen activator. A much higher urokinase-like immunoreactivity was found in the uterine fluid from IUD-users than from non-users. The fibrinolytic activity of the uterine fluid, which in contrast to that of the endometrium is known to be depressed in IUD-users, was inhibited by an antiserum against the tissue activator but only weakly influenced by an antiserum against urokinase. This indicates the presence of urokinase inhibitors in the uterine fluid of IUD-users with a capacity to inhibit the enzymatic activity of the urokinase-like plasminogen activator.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0010-7824
pubmed:author
pubmed:issnType
Print
pubmed:volume
23
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
435-45
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
Effect of IUD on urokinase-like immunoreactivity and plasminogen activators in human uterine fluid.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't