Linked Life Data

7022172

Source:http://linkedlifedata.com/resource/pubmed/id/7022172

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1981-10-25
pubmed:abstractText
The amount and quality of DNA synthesized in excision-defective strains of yeast was assayed using alkaline sucrose gradients. It was observed that, in such strains, there was less newly synthesized DNA in irradiated cells and that this material was in smaller pieces than in unirradiated controls. The molecular weight was inversely proportional to dose. The low molecular weight DNA chased into normally high molecular weight material during a post-pulse incubation period. This chase was inhibited by higher doses of UV, by hydroxyurea, and required the function of the RAD18 gene. The RAD6 gene function was necessary to prevent degradation of template DNA in irradiated excision-defective strains.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0027-5107
pubmed:author
pubmed:issnType
Print
pubmed:volume
82
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
69-85
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
DNA synthesis in UV-irradiated yeast.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't