Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1981-8-10
pubmed:abstractText
The prognostic significance of pre- and post-transplant B and T cell antibodies was studied in 183 cadaver kidney transplantations. Our results confirm previous reports that a successful kidney transplantation can be carried out in spite of a positive crossmatch due to B cell antibodies. However, it is doubtful whether such antibodies have a protective effect. The success rate seemed to be higher only in patients with preformed cold antibodies. The occurrence and persistence of allogeneic anti-donor antibodies directed against T cells was significantly associated with an unfavourable graft prognosis. Patients with post-transplant anti-donor B cell antibodies had lower (but not significantly) graft survival rates. These findings provide additional evidence for a crucial role of anti-donor antibodies in kidney graft outcome.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0071-2736
pubmed:author
pubmed:issnType
Print
pubmed:volume
17
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
478-82
pubmed:dateRevised
2008-2-21
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
Prognostic significance of B and T cell antibodies in kidney transplantation.
pubmed:publicationType
Journal Article