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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
1981-8-10
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pubmed:abstractText |
The prognostic significance of pre- and post-transplant B and T cell antibodies was studied in 183 cadaver kidney transplantations. Our results confirm previous reports that a successful kidney transplantation can be carried out in spite of a positive crossmatch due to B cell antibodies. However, it is doubtful whether such antibodies have a protective effect. The success rate seemed to be higher only in patients with preformed cold antibodies. The occurrence and persistence of allogeneic anti-donor antibodies directed against T cells was significantly associated with an unfavourable graft prognosis. Patients with post-transplant anti-donor B cell antibodies had lower (but not significantly) graft survival rates. These findings provide additional evidence for a crucial role of anti-donor antibodies in kidney graft outcome.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0071-2736
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
17
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
478-82
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pubmed:dateRevised |
2008-2-21
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pubmed:meshHeading |
pubmed-meshheading:7017693-Antibodies,
pubmed-meshheading:7017693-B-Lymphocytes,
pubmed-meshheading:7017693-Graft Survival,
pubmed-meshheading:7017693-Humans,
pubmed-meshheading:7017693-Kidney Transplantation,
pubmed-meshheading:7017693-Prognosis,
pubmed-meshheading:7017693-T-Lymphocytes,
pubmed-meshheading:7017693-Temperature,
pubmed-meshheading:7017693-Time Factors,
pubmed-meshheading:7017693-Transplantation, Homologous,
pubmed-meshheading:7017693-Transplantation Immunology
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pubmed:year |
1980
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pubmed:articleTitle |
Prognostic significance of B and T cell antibodies in kidney transplantation.
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pubmed:publicationType |
Journal Article
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