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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1981-7-20
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pubmed:abstractText |
A coordinated clinical trial (phase II) of preparation VM-26 supplied by Sandos (Switzerland) was carried out at 5 clinics in a total of 61 patients with lymphoma. Two regimens of VM-26 administration were employed: (1) 5-day courses of 30 mg/m2 iv with 7-14 day intervals, or (2) two injections of 50 mg/m2 a week, within 4-6 weeks, depending on drug tolerance Out of 15 children with Hodgkin's disease, 50% of cases showed complete or partial remission. Out of 27 adults with Hodgkin's disease, response was registered in 69.9 and a pronounced effect--in 1 26.1%. Out of 14 patients with lymphosarcomas, response was observed in 78.5 and a pronounced effect--in 57.2%. Toxic effect was not the cause of treatment suspension in most cases.
|
pubmed:language |
rus
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0507-3758
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
27
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
82-7
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:7015693-Adolescent,
pubmed-meshheading:7015693-Adult,
pubmed-meshheading:7015693-Aged,
pubmed-meshheading:7015693-Child,
pubmed-meshheading:7015693-Child, Preschool,
pubmed-meshheading:7015693-Clinical Trials as Topic,
pubmed-meshheading:7015693-Hodgkin Disease,
pubmed-meshheading:7015693-Humans,
pubmed-meshheading:7015693-Infant,
pubmed-meshheading:7015693-Lymphoma,
pubmed-meshheading:7015693-Lymphoma, Non-Hodgkin,
pubmed-meshheading:7015693-Middle Aged,
pubmed-meshheading:7015693-Podophyllotoxin,
pubmed-meshheading:7015693-Teniposide,
pubmed-meshheading:7015693-Time Factors
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pubmed:year |
1981
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pubmed:articleTitle |
[Use of preparation VM 26 (epipodophyllotoxin) for treating lymphomas in children and adults].
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
English Abstract,
Controlled Clinical Trial
|