Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1981-7-20
pubmed:abstractText
When neuroblastoma cells bearing neurites are incubated with colchicine or Nocodazole, the cytoplasmic microtubules are depolymerized and concomitantly the neurites retract. We report here that cytochalasin separates the two effects of these drugs: it quantitatively inhibits neurite retraction but does not inhibit microtubule assembly. The neurites that remain contain intermediate filaments and actin but are devoid of microtubules. Depletion of cellular ATP also blocks neurite retraction induced by colchicine or Nocodazole, but some assembled microtubules persist under these conditions. The results suggest that neurite retraction is an active cell process.
pubmed:grant
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/7014572-11221, http://linkedlifedata.com/resource/pubmed/commentcorrection/7014572-13986422, http://linkedlifedata.com/resource/pubmed/commentcorrection/7014572-200367, http://linkedlifedata.com/resource/pubmed/commentcorrection/7014572-229960, http://linkedlifedata.com/resource/pubmed/commentcorrection/7014572-4322607, http://linkedlifedata.com/resource/pubmed/commentcorrection/7014572-4352661, http://linkedlifedata.com/resource/pubmed/commentcorrection/7014572-4515617, http://linkedlifedata.com/resource/pubmed/commentcorrection/7014572-498277, http://linkedlifedata.com/resource/pubmed/commentcorrection/7014572-5061947, http://linkedlifedata.com/resource/pubmed/commentcorrection/7014572-5166556, http://linkedlifedata.com/resource/pubmed/commentcorrection/7014572-5273449, http://linkedlifedata.com/resource/pubmed/commentcorrection/7014572-5273894, http://linkedlifedata.com/resource/pubmed/commentcorrection/7014572-570461, http://linkedlifedata.com/resource/pubmed/commentcorrection/7014572-6893016, http://linkedlifedata.com/resource/pubmed/commentcorrection/7014572-6893454, http://linkedlifedata.com/resource/pubmed/commentcorrection/7014572-6933529, http://linkedlifedata.com/resource/pubmed/commentcorrection/7014572-7191423, http://linkedlifedata.com/resource/pubmed/commentcorrection/7014572-7350166, http://linkedlifedata.com/resource/pubmed/commentcorrection/7014572-7407915, http://linkedlifedata.com/resource/pubmed/commentcorrection/7014572-783172, http://linkedlifedata.com/resource/pubmed/commentcorrection/7014572-787987
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0021-9525
pubmed:author
pubmed:issnType
Print
pubmed:volume
89
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
157-61
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
Cytochalasin separates microtubule disassembly from loss of asymmetric morphology.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.