Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1981-3-17
pubmed:abstractText
It has been shown that five alkylnitrites are mutagens by the Salmonella/microsome assay. n-Propyl-, n-butyl, iso-butyl and amyl-nitrite are direct mutagens on TA 1535; sec-butyl-nitrite is mutagen on TA 1535 only following metabolic activation by Aroclor-induced rat liver homogenate. Because of the known correlation between mutagenicity and carcinogenicity, we believe that amyl-nitrite and iso-butyl-nitrite, which are used as human drugs, should be tested for carcinogenicity in animals; in the meanwhile, their use should be allowed only in emergencies.
pubmed:language
ita
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0037-8771
pubmed:author
pubmed:issnType
Print
pubmed:day
30
pubmed:volume
56
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
816-20
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
[Mutagenicity of alkylnitrites in the Salmonella test].
pubmed:publicationType
Journal Article, English Abstract