Linked Life Data

7000392

Source:http://linkedlifedata.com/resource/pubmed/id/7000392

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
1981-1-29
pubmed:abstractText
We evaluated a new homogeneous enzyme immunoassay of thyroxine with use of a discrete analyzer (the ABA-100 Bichromatic Analyzer), modified with an auxiliary dispenser assembly. The assay is based on inhibition of hydrolysis of the substrate, acetyl-beta-(methylthio)choline iodide, by acetylcholinesterase (acetylcholine hydrolase; EC 3.1.1.7). Thyroxine covalently linked to a cholinesterase inhibitor irreversibly inhibits acetylcholinesterase, but if this thyroxine conjugate is bound to antibody it is not inhibitory. Seventy-five patients' samples may be analyzed in 1 h of instrument time. Precision and accuracy are excellent, results correlate well with those by radioimmunoassay, and there were no instances of confused clinical interpretation resulting from use of the proposed assay.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0009-9147
pubmed:author
pubmed:issnType
Print
pubmed:volume
26
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1723-6
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
Evaluation of a new homogeneous enzyme inhibitor immunoassay of serum thyroxine with use of a bichromatic analyzer.
pubmed:publicationType
Journal Article