Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1980-5-30
|
pubmed:abstractText |
Ten normocalcemic critically ill patients who had experienced a decrease in cardiac index greater than or equal to 0.5 liter/min/m2 after incremental changes of PEEP received 7 mg/kg of CaCl2 as a slow iv bolus, followed by an infusion of 20 mg/kg CaCl2 over 60 min. Hemodynamic pressures and flow, oxygen uptake and transport, and blood chemistry variables were determined over a 120-min period. The results indicated that: (1) hemodynamic variables were not affected except for left ventricular stroke work index and mean blood pressure, which increased slightly; (2) both serum calcium and ionized calcium concentrations increased significantly, sometimes to dangerous levels; (3) colloid osmotic pressure and hemoglobin levels decreased slightly but consistently. In conclusion, CaCl2 administration failed to improve hemodynamic function depressed by PEEP. If CaCl2 can play a relevant role in the management of cardiovascular depression, further identification of appropriate doses and patients is necessary.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
AIM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0090-3493
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
8
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
209-12
|
pubmed:dateRevised |
2007-11-15
|
pubmed:meshHeading |
pubmed-meshheading:6987039-Aged,
pubmed-meshheading:6987039-Blood Pressure,
pubmed-meshheading:6987039-Calcium,
pubmed-meshheading:6987039-Calcium Chloride,
pubmed-meshheading:6987039-Cardiac Output,
pubmed-meshheading:6987039-Critical Care,
pubmed-meshheading:6987039-Heart Rate,
pubmed-meshheading:6987039-Hemodynamics,
pubmed-meshheading:6987039-Hemoglobins,
pubmed-meshheading:6987039-Humans,
pubmed-meshheading:6987039-Middle Aged,
pubmed-meshheading:6987039-Oxygen Consumption,
pubmed-meshheading:6987039-Positive-Pressure Respiration
|
pubmed:year |
1980
|
pubmed:articleTitle |
Calcium chloride administration in normocalcemic critically ill patients.
|
pubmed:publicationType |
Journal Article
|