Linked Life Data

6975547

Source:http://linkedlifedata.com/resource/pubmed/id/6975547

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1982-1-28
pubmed:abstractText
Effects of small iv doses of 1.25-dihydroxy- and 24.25-dihydroxy-vitamin D3 (a microgram) were studied in 10 normal subjects. Injection of 1.25 (OH)2D3 was associated with small but significant increases in plasma calcium and phosphate but plasma levels of immunoreactive parathyroid hormone (iPTH) and calcitonin (iCT) did not change. The administration of 24.25 (OH)2D3 was associated with comparable decreases in plasma calcium and a small and transient decrease in plasma iPTH. Plasma levels of iCT did not change. 24.25 (OH)2D3 also significantly increased glomerular filtration rate and decreased the urinary excretion of noradrenaline, in contrast to 1.25 (OH)2D3 which had no effect on these variables. The rapid infusion of calcium significantly decreased levels of iPTH. We conclude that small doses of 1.25 (OH)2D3 and 24.25 (OH)2D3 have little, if any, direct effect on the secretion of PTH and CT in man.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0001-5598
pubmed:author
pubmed:issnType
Print
pubmed:volume
98
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
619-24
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
Comparison of acute effects of 1.25- and 24.25-dihydroxy-vitamin D3 in normal subjects.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't