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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8
|
pubmed:dateCreated |
1981-12-21
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pubmed:abstractText |
Twenty-five pigs inoculated with African Swine fever virus were studied for the development of changes in lymphocyte numbers and function. The results indicated that lymphopenia and decreased percentage of circulating T-lymphocytes occurred as early as 7 days after the pigs were inoculated. These were accompanied by depressed lymphocyte function, as measured by mitogen- or antigen-induced blastogenesis. There were proportionately greater decreases in T-lymphocyte numbers and function than were found for B-lymphocytes. Studies of phagocytic cell function revealed decreased phagocytic function for peripheral blood monocytes and unchanged (normal) neutrophil function. Depressed T-lymphocyte function occurred in pigs with acute and subacute infections, indicating depression of cellular immune function.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
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pubmed:issn |
0002-9645
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
42
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
1335-41
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6975049-Acid Phosphatase,
pubmed-meshheading:6975049-African Swine Fever,
pubmed-meshheading:6975049-African Swine Fever Virus,
pubmed-meshheading:6975049-Animals,
pubmed-meshheading:6975049-Antibodies, Viral,
pubmed-meshheading:6975049-B-Lymphocytes,
pubmed-meshheading:6975049-Immunity, Cellular,
pubmed-meshheading:6975049-Leukocyte Count,
pubmed-meshheading:6975049-Lymphocyte Activation,
pubmed-meshheading:6975049-Lymphocytes,
pubmed-meshheading:6975049-Phagocytosis,
pubmed-meshheading:6975049-Swine,
pubmed-meshheading:6975049-T-Lymphocytes
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pubmed:year |
1981
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pubmed:articleTitle |
Lymphocyte function and cell-mediated immunity in pigs with experimentally induced African swine fever.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
|