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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1981-9-25
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pubmed:abstractText |
The addition of a T-cell growth-promoting medium (PHA-TCM) to culture conditions that support growth of multi-lineage hemopoietic colonies enhances the proliferation of cells with lymphoid morphology within these colonies. These cells were identified as T lymphocytes by their ability to form rosettes with SRBC and their reaction with monoclonal antibodies (OKT3, OKT4) directed against T-cell-specific surface components. They continue to proliferate extensively under the influence of PHA-TCM after transfer of mixed colonies into liquid suspension culture. Supportive evidence for a common progenitor of myeloid and lymphoid cells within single mixed colonies is provided by Y-chromatin body analysis of E-rosette positive and negative cells in colonies grown in cocultures of male and female bone marrow cells.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
|
pubmed:issn |
0006-4971
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
58
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
402-5
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6972790-Cell Division,
pubmed-meshheading:6972790-Cells, Cultured,
pubmed-meshheading:6972790-Erythrocytes,
pubmed-meshheading:6972790-Female,
pubmed-meshheading:6972790-Granulocytes,
pubmed-meshheading:6972790-Hematopoietic Stem Cells,
pubmed-meshheading:6972790-Humans,
pubmed-meshheading:6972790-Male,
pubmed-meshheading:6972790-Rosette Formation,
pubmed-meshheading:6972790-T-Lymphocytes,
pubmed-meshheading:6972790-Y Chromosome
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pubmed:year |
1981
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pubmed:articleTitle |
Identification of T lymphocytes in human mixed hemopoietic colonies.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|