Linked Life Data

6957530

Source:http://linkedlifedata.com/resource/pubmed/id/6957530

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1982-12-21
pubmed:abstractText
To determine whether the plasma ferritin assay reliably reflects body iron stores, as determined by the presence of stainable iron in the marrow, 63 iron-deficient patients were serially studied after receiving a total dose infusion of iron dextran (Imferon). In 58% (Group I) anemia did not recur. In 19% (Group II) classical iron deficiency was present with low plasma ferritin levels, reduced transferrin saturation and absence of stainable iron in the marrow. In 13% (Group III) evolving iron deficiency was seen with low plasma ferritin level but normal hemoglobin and transferrin saturation. The development of overt iron deficiency was associated with a fall in the transferrin saturation and absence of stainable iron in the marrow. In the remaining 10% (Group IV) the initially raised plasma ferritin fell in parallel with the developing anemia, reduction in transferrin saturation and absence of reticuloendothelial marrow iron. These studies demonstrated that in the development of iron deficiency anemia following total dose infusion of iron dextran (Imferon) there was a relationship (r = 0.9625; p less than 0.05) between decreasing body iron stores and falling plasma ferritin levels. Accordingly, the latter measurement should replace bone marrow studies carried out for this purpose.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0025-7850
pubmed:author
pubmed:issnType
Print
pubmed:volume
13
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
309-21
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
The plasma ferritin level as a reliable index of body iron stores following intravenous iron dextran.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't