Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1980-11-24
pubmed:abstractText
We searched for possible immunogenetic markers in steroid-responsive nephrotic syndrome of childhood (SRNS). The incidence of HLA-DRw7 was significantly greater in SRNS patients than in controls (71% in patients, 29.8% in controls, P < 0.005). The HLA-A and -B locus antigens occurred in normal frequencies. The relative risk factor for HLA-DRw7 in SRNS was 5.9. This report failed to show a relationship between HLA-DRw7 and atopy, use of alkylating agents or occurrence of relapse after remission induced by these agents. We believe that SRNS may be an immunologic disorder whose pathogenesis is related to an MHC-linked Ir gene.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0301-0430
pubmed:author
pubmed:issnType
Print
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
71-4
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
HLA-DRw7 and steroid-responsive nephrotic syndrome of childhood.
pubmed:publicationType
Journal Article