Linked Life Data

6891066

Source:http://linkedlifedata.com/resource/pubmed/id/6891066

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1983-2-25
pubmed:abstractText
Haloperidol-induced catalepsy in rats is reduced by low dose baclofen and is potentiated by high dose baclofen. This biphasic behavioral effect is consistent with reported differences between presynaptic and postsynaptic GABA receptors. Low dose baclofen could have an anti-cholinergic effect by activating presynaptic GABA receptors that inhibit the release of acetylcholine. High dose baclofen could have an anti-dopamine effect by activating postsynaptic GABA receptors that inhibit the firing of dopamine neurons.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0091-3057
pubmed:author
pubmed:issnType
Print
pubmed:volume
17
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
855-6
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Biphasic dose-response effect of baclofen on haloperidol catalepsy in the rat.
pubmed:publicationType
Journal Article