Linked Life Data

6885315

Source:http://linkedlifedata.com/resource/pubmed/id/6885315

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
1983-10-28
pubmed:abstractText
Twenty-four normal human subjects were studied before and after one week of treatment with 0.1% topical dexamethasone. Intraocular pressure, corneal thickness and endothelial cell size were measured. The flow of aqueous humor and the endothelial permeability to fluorescein were determined using fluorophotometry. In addition, the relationship between the initial location of an iontophoretic depot of fluorescein and its kinetics was studied. There was a small and significant increase in intraocular pressure in the eyes treated with dexamethasone but no significant change in corneal thickness, endothelial permeability or the rate of aqueous humor flow. The elimination of fluorescein from the eye was slightly higher when the fluorescein depot was placed adjacent to the superior limbus than when the depot was placed in the central cornea. Smaller right to left differences were observed when fluorescein was placed peripherally than when it was placed centrally. The increased precision with peripheral placement is probably due to the improved signal-to-noise ratio for fluorescence measurements of the anterior chamber through the unstained cornea.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0146-0404
pubmed:author
pubmed:issnType
Print
pubmed:volume
24
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1307-11
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Absence of an effect of topical dexamethasone on endothelial permeability and flow of aqueous humor.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't