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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4613
|
| pubmed:dateCreated |
1983-9-20
|
| pubmed:abstractText |
Rats of line LC2-Hi that drank about 50 milliliters of a highly palatable saccharin solution daily for 28 consecutive days did not show morphine analgesia or an opioid form of stress-induced analgesia and were not responsive to naloxone. These findings support the idea that chronically elevated saccharin intake may cause increased release and utilization of endogenous opiates.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Aug
|
| pubmed:issn |
0036-8075
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
26
|
| pubmed:volume |
221
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
871-3
|
| pubmed:dateRevised |
2008-11-21
|
| pubmed:meshHeading |
pubmed-meshheading:6879185-Animals,
pubmed-meshheading:6879185-Drug Tolerance,
pubmed-meshheading:6879185-Endorphins,
pubmed-meshheading:6879185-Morphine,
pubmed-meshheading:6879185-Pain,
pubmed-meshheading:6879185-Rats,
pubmed-meshheading:6879185-Saccharin,
pubmed-meshheading:6879185-Stress, Physiological
|
| pubmed:year |
1983
|
| pubmed:articleTitle |
Morphine tolerance in genetically selected rats induced by chronically elevated saccharin intake.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|