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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1983-8-11
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pubmed:abstractText |
The composition of immune complexes (IC) found in 28 patients with HBsAg positive and negative acute and chronic hepatitis was analysed. Components were defined in PEG-precipitated material isolated by preparative ultracentrifugation on linear sucrose density gradients and analysed by the Ouchterlony plate technique and by the radioimmunoassay of hepatitis B virus markers. Sedimentation rate ranged from 8 to 19s in the serum of patients with chronic hepatitis, whereas heavier IC (greater than 19s) were present in the active phase of the disease. The participation of hepatitis B virus in acute hepatitis was shown by the presence of its antigens. In contrast, a low incidence of vital components was seen in IC of chronic active hepatitis and liver cirrhosis. Thus, other causes must contribute to the formation of IC in chronic liver disease.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0141-2760
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
10
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
179-83
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6864764-Acute Disease,
pubmed-meshheading:6864764-Antigen-Antibody Complex,
pubmed-meshheading:6864764-Chronic Disease,
pubmed-meshheading:6864764-Hepatitis, Viral, Human,
pubmed-meshheading:6864764-Hepatitis B Surface Antigens,
pubmed-meshheading:6864764-Humans,
pubmed-meshheading:6864764-Liver Cirrhosis
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pubmed:year |
1983
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pubmed:articleTitle |
Characterization of the circulating immune complexes in acute and chronic liver diseases.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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