Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1983-8-26
pubmed:abstractText
Human parotid saliva contains agglutinins which bind to the surface of streptococci and induce the formation of bacterial aggregates. Bacterial aggregation can be blocked by proteins released from viable PMNs and platelets or by sonic extracts prepared from these cells. PMN and platelet inhibitors display characteristic differences in molecular weight, protease, and temperature sensitivity. The mechanism of action of the inhibitors appears to involve a direct interaction with the salivary agglutinins rather than with the bacteria. It is thus possible that PMN and platelet-derived products might modulate saliva-mediated bacterial aggregation and thereby influence the course of infections in the oral cavity.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0360-3997
pubmed:author
pubmed:issnType
Print
pubmed:volume
7
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
133-44
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Modulation of bacterial aggregation by PMN and platelet extracts.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.