Linked Life Data

6852836

Source:http://linkedlifedata.com/resource/pubmed/id/6852836

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1983-7-15
pubmed:abstractText
Multicell spheroids are useful as in vitro models for certain nodular tumors. Spheroids may contain subpopulations of cells that are necrotic, hypoxic, and redistributed through the cell cycle, and the relative fractions of these subpopulations can change as the spheroids grow. As a result, spheroids of different sizes may respond differently to any given treatment. For experimental studies it is important to use populations of spheroids of homogeneous size. Here we report the design and use of a sedimentation column that uses precision woven screen to obtain homogeneously sized populations of multicell spheroids quickly, accurately, aseptically, and reproducibly. This device may be applied in other biological fields also where separation of cell aggregates of a specific size is required.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0073-5655
pubmed:author
pubmed:issnType
Print
pubmed:volume
19
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
361-6
pubmed:dateRevised
2009-11-11
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Use of a sedimentation column to obtain uniformly sized populations of multicell spheroids.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S.