Linked Life Data

6825057

Source:http://linkedlifedata.com/resource/pubmed/id/6825057

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1983-4-21
pubmed:abstractText
A case of mucoepidermoid carcinoma of the bronchus with low grade histologic features exhibited an aggressive biological behavior. All gross, microscopic, and ultrastructural features were those of a morphologically low grade mucoepidermoid carcinoma. Grossly, the lesion was an exophytic endobronchial mass; microscopically, it contained sheets of monomorphic cells with well-formed mucus glands, no mitoses, and no necrosis; and ultrastructurally, it consisted of numerous goblet cells and mitochondria- and glycogen-rich cells with well-formed microvilli. However, the patient developed widespread metastases to skin, subcutaneous tissue, femur, vertebral column, and pericardium and died two months after the primary endobronchial tumor was excised. The metastases, like the primary tumor, had the appearance of "low grade" mucoepidermoid carcinoma. Explants of the original tumor grown in nude mice for three months showed persistence of the low-grade morphologic pattern. Although metastases are known to occur frequently from high-grade lesions, widespread metastases from histologically low-grade lesions have not previously been reported. Low-grade histologic features of mucoepidermoid carcinoma are not necessarily then indicative of low-grade biological behavior.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0008-543X
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
51
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1505-9
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
"Low grade" mucoepidermoid carcinoma of the bronchus with "high grade" biological behavior.
pubmed:publicationType
Journal Article, Case Reports