Linked Life Data

6820419

Source:http://linkedlifedata.com/resource/pubmed/id/6820419

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1983-6-10
pubmed:abstractText
Children with phenylketonuria (PKU) are treated with semi-synthetic diets restricted in phenylalanine. Low-phenylalanine or phenylalanine-free formulae provide the majority of protein and energy in the diet while phenylalanine requirements are met by low-protein natural foods. Because of the restriction of natural protein sources in this diet, the study assessed the zinc nutrition of 22 treated children with PKU (aged from 1 month to 8 1/2 years) and correlated linear growth with zinc status. The mean (+/- SE) plasma zinc concentration of the PKU population was 66.6 +/- 3.3 micrograms/dl. The mean (+/- SE) hair zinc concentration was 70.2 +/- 11.5 micrograms/g. The mean plasma and hair zinc concentrations of the PKU population were significantly different (p less than 0.05) when compared with mean (+/- SE) normal values of 84.2 +/- 2.9 micrograms/dl and 130.7 +/- 8.3 micrograms/g, respectively. The mean (+/- SD) dietary zinc intake of 10 PKU patients was 8.56 +/- 2.68 mg/day. No significant differences (p less than 0.123) were found when the mean zinc intake was compared with National Academy of Sciences Recommended Dietary Allowance for age of 10 mg/day. No significant correlations were found when plasma and hair zinc concentrations were plotted with height percentiles. Further studies are required to assess the effects of zinc supplementation and the bioavailability of zinc from low-phenylalanine diets.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0141-8955
pubmed:author
pubmed:issnType
Print
pubmed:volume
5
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
107-10
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Zinc status and growth of children undergoing treatment for phenylketonuria.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't