Rat immunoglobulin delta heavy chain gene: nucleotide sequence derived from cloned cDNA.

Source:http://linkedlifedata.com/resource/pubmed/id/6819978

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Authors

Sire J, Jordan BR, Auffray C

Abstract

Rat immunoglobulin delta heavy-chain mRNA has been isolated. RNA blot analysis revealed that this mRNA with a length of 1.8 kb encodes for the secreted form of IgD. The corresponding cDNA was cloned in plasmid pBR322 and its sequence was determined. The hybrid plasmid contains a 775-bp insert comprising a partial C delta 1 sequence and complete C delta H, C delta 3, C delta DC and 3' untranslated sequences. Rat and mouse IgD amino acid sequences show striking homology in C delta 3 and C delta DC regions.

PMID
6819978

Publication types

Research Support, Non-U.S. Gov't