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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1978-10-27
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pubmed:abstractText |
The density of microtubules, T.D. (number of tubules/unit area) is highest in small crab nerve axons. After cooling of the nerve at 0 degrees C, the tubule density tends to zero (T.D. 2% of the normothermic value). Once the cooled nerves are returned in normothermia, the reconstitution of the microtubules is evidenced (T.D. = 90% of the initial normothermic value). Therefore cooling "depolymerizes" the tubules, whereas rewarming leads to their "repolymerization." These results definitely improve the interpretation of the birefringence decrease by cooling: as tubules and filaments contribute to the positive fraction of the total positive birefringence, their depolymerization by cooling explains to a large extent the decrease in total birefringence.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0022-3034
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
9
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
247-54
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading | |
pubmed:year |
1978
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pubmed:articleTitle |
Hypothermic decrease in microtubule density and birefringence in unimyelinated axons.
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pubmed:publicationType |
Journal Article
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