Linked Life Data

6819149

Source:http://linkedlifedata.com/resource/pubmed/id/6819149

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
1983-4-21
pubmed:abstractText
Two distinct antibodies raised against quail thymocytes were used in an indirect immunofluorescence assay to analyze the expression of differentiation antigens on T lineage cells in embryonic and newly hatched quail. (a) A rabbit serum, anti-AT-65, that has been previously shown to immunoprecipitate a protein of apparently 65-70 kDa from quail and chick thymocytes, reacts with both thymic and peripheral T cells. The polyspecificity of this pan-avian T cell reagent can be dissected by absorption and includes reactivities against two distinct antigenic entities. One of these is restricted to thymocytes whereas the other is also expressed on peripheral T cells. (b) A monoclonal antibody, a-TD1, defines the population of cortical thymocytes and does not react with peripheral T cells. Binding assays during the embryonic development of the T lineage reveal that specific surface markers are expressed 36 h following the seeding of lymphoid precursor cells to the thymic rudiment, suggesting their early commitment in this lymphoid microenvironment. T cells are also shown to be exported precociously to the embryonic splenic compartment.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0014-2980
pubmed:author
pubmed:issnType
Print
pubmed:volume
12
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1047-50
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Tissue distribution and ontogenetic emergence of differentiation antigens on avian T cells.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't