Linked Life Data

6806104

Source:http://linkedlifedata.com/resource/pubmed/id/6806104

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1982-8-14
pubmed:abstractText
Benoxaprofen has three pharmacological activities which may relate to its clinical activity profile. The most important of these for anti-inflammatory therapy is the regulation of directional monocyte movement in response to a stimulus but the inhibitory activity against lipoxygenase may be of considerable relevance in the treatment of asthma. The relatively weak inhibitory action on prostaglandin synthetase probably confers clinical benefit with a reduced potential to cause severe gastric side effects. Benoxaprofen is an inhibitor pf the lipoxygenase enzyme which converts arachidonic acid to hydroxy derivatives and the leukotrienes. These products are potent pharmacological agents with potentially important roles in inflammation and hypersensitivity disorders.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0140-1610
pubmed:author
pubmed:issnType
Print
pubmed:volume
5
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
61-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
The pharmacology of benoxaprofen with particular to effects on lipoxygenase product formation.
pubmed:publicationType
Journal Article, In Vitro