Linked Life Data

6805502

Source:http://linkedlifedata.com/resource/pubmed/id/6805502

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1982-8-14
pubmed:abstractText
1. A "new" carbon radioisotope, 11C, for use in nutritional studies is presented. It has a 20 min half-life, and decays by positron emission giving annihilation photons of 511 keV energy (Wolf & Redvanly, 1977). Thus repeated studies can be made with short time intervals and the distribution of radioactivity in the experimental animal can be detected externally. 2. 11C was produced with a tandem Van de Graaff accelerator and L-[me-11C]methionine was synthesized and used in model experiments in the pig. The tracer was administered intravenously through a catheter in the jugular vein of pigs weighing between 40 and 100 kg. In a series of experiments, one pig received a low-methionine diet supplemented with DL-methionine to give three different levels of methionine intake. 3. The radioactivity distribution between liver and muscle was measured as a function of time by external detector for 2-3 h after administration. Blood and exhaled CO2 were sampled and measured for radioactivity. 4. The results indicate that 11C is a useful radionuclide in nutritional studies in intact large domestic animals.U
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0007-1145
pubmed:author
pubmed:issnType
Print
pubmed:volume
47
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
537-45
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Short-lived radionuclides in nutritional physiology. A model study with L-[Me-11C]methionine in the pig.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't