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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
1981-10-25
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pubmed:abstractText |
Seven dogs with diabetic ketoacidosis were treated initially with lactated Ringer's solution or 0.45% NaCl solution subcutaneously or intravenously and low doses of regular (crystalline) insulin administered intramuscularly every hour until the blood glucose concentration decreased to less than 250 mg/dl. For dogs weighing less than or equal to 10 kg, the initial dose was 2 units and the hourly doses were 1 unit. For dogs weighing greater than 10 kg, the initial dosage was 0.25 units/kg of body weight, and the dosage for hourly injections was 0.1 units/kg. The mean hourly decrease of the blood glucose concentration for all 7 dogs was 87.6 mg/dl. The mean period of treatment required was 4.1 hours. Late hypoglycemia did not develop in any dog, but the serum potassium concentration decreased 0.4 to 1.0 mEq/L. The results suggested that low-dose intramuscular regular insulin therapy for treatment of diabetic ketoacidosis is an effective alternative to conventional regular insulin therapy in dogs.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0003-1488
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
178
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
561-4
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:6790505-Animals,
pubmed-meshheading:6790505-Blood Glucose,
pubmed-meshheading:6790505-Diabetic Ketoacidosis,
pubmed-meshheading:6790505-Dog Diseases,
pubmed-meshheading:6790505-Dogs,
pubmed-meshheading:6790505-Female,
pubmed-meshheading:6790505-Injections, Intramuscular,
pubmed-meshheading:6790505-Insulin,
pubmed-meshheading:6790505-Male,
pubmed-meshheading:6790505-Potassium
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pubmed:year |
1981
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pubmed:articleTitle |
Low-dose intramuscular insulin therapy for diabetic ketoacidosis in dogs.
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pubmed:publicationType |
Journal Article
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