Linked Life Data

6775619

Source:http://linkedlifedata.com/resource/pubmed/id/6775619

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1980-12-18
pubmed:abstractText
We have studied the effects of prostacyclin (PGI2) infusions in two different types of angina pectoris, i.e. effort and spontaneous angina. Contrary to sublingual nitroglycerin, intravenous infusions of PGI2 at a dose of 5 or 10 ng/kg/min offered no protection against effort anginal attacks precipitated by atrial pacing. On the other hand, in recurrent attacks of spontaneous angina at rest, infusion of PGI2 at a dose of 5 ng/kg/min led to sustained and long-lasting improvement as manifested by reduction of both anginal attacks and nitroglycerin intake. Different pathogenic mechanisms underlying the two types of angina studied could explain the results obtained. Prostacyclin might be of threapeutic interest in attacks of angina pectoris precipitated by redution of oxygen delivery to the myocardium rather than increased oxygen demand.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0098-6127
pubmed:author
pubmed:issnType
Print
pubmed:volume
8
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
7-11
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
Prostacyclin for acute coronary insufficiency.
pubmed:publicationType
Journal Article