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rdf:type |
|
|
lifeskim:mentions |
|
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pubmed:issue |
5
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|
pubmed:dateCreated |
1980-6-27
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|
pubmed:abstractText |
The effect of neonatally initiated injections of anti-mu serum on immunity to reinfection with Schistosoma mansoni in the rat was investigated in vitro and in vivo. Anti-mu treatment resulting in a profound depression of immunoglobulin synthesis dramatically decreased immunity to reinfection assessed by worm recovery technique. Complement-dependent antibody, IgG2a antibody-eosinophil-mediated and IgE-macrophage cytotoxicity reactions were in parallel markedly reduced. These results show the prominent role played by antibody-dependent mechanisms in immunity to schistosomes in the rat.
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
AIM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0022-1767
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
124
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|
pubmed:owner |
NLM
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|
pubmed:authorsComplete |
Y
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pubmed:pagination |
2373-7
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|
pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6767787-Animals,
pubmed-meshheading:6767787-Animals, Newborn,
pubmed-meshheading:6767787-Antibodies,
pubmed-meshheading:6767787-Cytotoxicity, Immunologic,
pubmed-meshheading:6767787-Female,
pubmed-meshheading:6767787-Immune Sera,
pubmed-meshheading:6767787-Immunoglobulin D,
pubmed-meshheading:6767787-Immunoglobulin E,
pubmed-meshheading:6767787-Immunoglobulin G,
pubmed-meshheading:6767787-Immunoglobulin Heavy Chains,
pubmed-meshheading:6767787-Immunoglobulin mu-Chains,
pubmed-meshheading:6767787-Injections, Intraperitoneal,
pubmed-meshheading:6767787-Male,
pubmed-meshheading:6767787-Rabbits,
pubmed-meshheading:6767787-Rats,
pubmed-meshheading:6767787-Rats, Inbred Strains,
pubmed-meshheading:6767787-Schistosoma mansoni,
pubmed-meshheading:6767787-Schistosomiasis
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pubmed:year |
1980
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|
pubmed:articleTitle |
Effect of neonatal injection of anti-mu antibodies on immunity to schistosomes (S. mansoni) in the rat.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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