Linked Life Data

6764140

Source:http://linkedlifedata.com/resource/pubmed/id/6764140

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1983-9-23
pubmed:abstractText
The onset of puberty and sexual maturation were studied in female rats that had been hemidecorticated (HD) during the neonatal period (1-3 days old). Hemidecorticate and control rats submitted to photostimulation (14 h light: 10 h dark) had earlier and better synchronized vaginal opening (VO) than rats raised under natural light (12 h light: 12 h dark). HD rats maintained under 14 h light: 10 h dark had vaginal opening 4-5 days earlier than their controls under the same light conditions. Peaks of plasma gonadotrophin (LH) were observed in hemidecorticate animals 10 days (30th day of life) earlier than in the controls (40th day). These LH peaks were preceded by higher adenohypophyseal and uterine weights at 25 and 30 days of age. The estrous cycles observed in adult rats that were hemidecorticated during the neonatal period were similar to that of intact rats. These results suggest that hemidecortication induces early puberty. This effect could be due to accelerated maturation of the ovaries probably due to the unrestricted activity of the medial basal hypothalamus, which in turn might activate the hypothalamic mechanisms that trigger puberty.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0100-879X
pubmed:author
pubmed:issnType
Print
pubmed:volume
15
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
367-75
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Puberty and sexual maturation in hemidecorticate female rats.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't