| pubmed-article:6753894 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:6753894 | lifeskim:mentions | umls-concept:C0087111 | lld:lifeskim |
| pubmed-article:6753894 | lifeskim:mentions | umls-concept:C0020538 | lld:lifeskim |
| pubmed-article:6753894 | lifeskim:mentions | umls-concept:C0006938 | lld:lifeskim |
| pubmed-article:6753894 | lifeskim:mentions | umls-concept:C0596545 | lld:lifeskim |
| pubmed-article:6753894 | lifeskim:mentions | umls-concept:C0205224 | lld:lifeskim |
| pubmed-article:6753894 | lifeskim:mentions | umls-concept:C0205225 | lld:lifeskim |
| pubmed-article:6753894 | lifeskim:mentions | umls-concept:C0443252 | lld:lifeskim |
| pubmed-article:6753894 | pubmed:dateCreated | 1983-1-19 | lld:pubmed |
| pubmed-article:6753894 | pubmed:abstractText | 1 Forty-one patients with primary (essential) hypertension were treated with captopril alone or in combination with hydrochlorothiazide for 12-36 months. 2 During an initial dose-titration period mean blood pressure fell from 174/111 mm Hg to 134/88 mm Hg supine and from 170/116 mm Hg to 126/93 mm Hg standing after 3 months' treatment. 3 During long-term treatment with unchanged or reduced doses of captopril or hydrochlorothiazide, or both, blood pressure remained substantially reduced. Mean supine blood pressure at 24 months was 136/90 mm Hg and at 36 months 138/90 mm Hg. 4 In 12 patients with clearly defined low renin (essential) hypertension initial blood pressure reduction was less than in patients with normal renin hypertension after 1 month's treatment (162/102 mm Hg v 143/92 mm Hg). After 24 months of treatment, however, the treatment results were similar in the two groups. 5 Except for one case of reversible proteinuria no serious side effects were seen during treatment periods of up to three years. 6 Captopril alone or in combination with hydrochlorothiazide seems to be an effective and safe drug in the long-term treatment of primary hypertension. | lld:pubmed |
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| pubmed-article:6753894 | pubmed:language | eng | lld:pubmed |
| pubmed-article:6753894 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6753894 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:6753894 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:6753894 | pubmed:issn | 0306-5251 | lld:pubmed |
| pubmed-article:6753894 | pubmed:author | pubmed-author:KarlbergB EBE | lld:pubmed |
| pubmed-article:6753894 | pubmed:author | pubmed-author:NilssonO ROR | lld:pubmed |
| pubmed-article:6753894 | pubmed:author | pubmed-author:AsplundJJ | lld:pubmed |
| pubmed-article:6753894 | pubmed:author | pubmed-author:WettreSS | lld:pubmed |
| pubmed-article:6753894 | pubmed:author | pubmed-author:OhmanK PKP | lld:pubmed |
| pubmed-article:6753894 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:6753894 | pubmed:volume | 14 Suppl 2 | lld:pubmed |
| pubmed-article:6753894 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:6753894 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:6753894 | pubmed:pagination | 133S-137S | lld:pubmed |
| pubmed-article:6753894 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:6753894 | pubmed:meshHeading | pubmed-meshheading:6753894-... | lld:pubmed |
| pubmed-article:6753894 | pubmed:year | 1982 | lld:pubmed |
| pubmed-article:6753894 | pubmed:articleTitle | Long-term experience of captopril in the treatment of primary (essential) hypertension. | lld:pubmed |
| pubmed-article:6753894 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:6753894 | lld:pubmed |
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