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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
1984-8-29
|
| pubmed:databankReference | |
| pubmed:abstractText |
Neighboring base-pairs are known to affect site-specific mutability. A previous analysis had suggested that such effects might decrease rapidly with distance. Here, however, we demonstrate a longer-range (unneighborly) base-pair effect on site-specific mutabilities: a single base-pair substitution substantially alters transition mutation rates at sites more than ten base-pairs away. DNA sequencing carried out during this analysis extends the known sequence of the rIIA cistron by 333 residues.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jun
|
| pubmed:issn |
0022-2836
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
25
|
| pubmed:volume |
176
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
239-49
|
| pubmed:dateRevised |
2000-12-18
|
| pubmed:meshHeading |
pubmed-meshheading:6748077-Base Composition,
pubmed-meshheading:6748077-Base Sequence,
pubmed-meshheading:6748077-DNA, Viral,
pubmed-meshheading:6748077-Genes, Viral,
pubmed-meshheading:6748077-Mutation,
pubmed-meshheading:6748077-Recombination, Genetic,
pubmed-meshheading:6748077-T-Phages,
pubmed-meshheading:6748077-Time Factors
|
| pubmed:year |
1984
|
| pubmed:articleTitle |
Modulation of mutation rates in bacteriophage T4 by a base-pair change a dozen nucleotides removed.
|
| pubmed:publicationType |
Journal Article
|