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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1984-8-13
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pubmed:abstractText |
Hyperprolactinaemia was induced in castrated, testosterone-treated male rats using ectopic pituitary grafts under the kidney capsules. After 6 weeks the absolute refractory period of stria terminalis neurones in these animals did not differ significantly from long-term castrated rats (mean = 1.72 vs 1.69 ms) in spite of the presence of normal testosterone concentrations. Gonadally intact animals, and sham-operated castrated animals treated with testosterone, showed by comparison the characteristic significantly shorter absolute refractory period normally associated with testosterone stimulation (mean = 1.15 and 1.08 ms respectively). These results provide the first demonstration that hyperprolactinaemia can abolish central sensitivity to testosterone.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0022-0795
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
102
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
109-13
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6736847-Amygdala,
pubmed-meshheading:6736847-Animals,
pubmed-meshheading:6736847-Castration,
pubmed-meshheading:6736847-Electrophysiology,
pubmed-meshheading:6736847-Hypothalamus,
pubmed-meshheading:6736847-Male,
pubmed-meshheading:6736847-Neural Conduction,
pubmed-meshheading:6736847-Neurons,
pubmed-meshheading:6736847-Pituitary Gland,
pubmed-meshheading:6736847-Prolactin,
pubmed-meshheading:6736847-Rats,
pubmed-meshheading:6736847-Rats, Inbred Strains,
pubmed-meshheading:6736847-Refractory Period, Electrophysiological,
pubmed-meshheading:6736847-Testosterone
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pubmed:year |
1984
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pubmed:articleTitle |
Hyperprolactinaemia abolishes sensitivity of stria terminalis neurones to testosterone.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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