pubmed-article:6732822 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:6732822 | lifeskim:mentions | umls-concept:C0023779 | lld:lifeskim |
pubmed-article:6732822 | lifeskim:mentions | umls-concept:C0033684 | lld:lifeskim |
pubmed-article:6732822 | lifeskim:mentions | umls-concept:C0042784 | lld:lifeskim |
pubmed-article:6732822 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
pubmed-article:6732822 | lifeskim:mentions | umls-concept:C0066924 | lld:lifeskim |
pubmed-article:6732822 | pubmed:issue | 2 | lld:pubmed |
pubmed-article:6732822 | pubmed:dateCreated | 1984-7-20 | lld:pubmed |
pubmed-article:6732822 | pubmed:abstractText | The effect of associated lipids and covalently bound fatty acids, and the contribution of serum albumin and secretory IgA to the viscosity of dog gastric mucus glycoprotein was investigated. Using a cone/plate viscometer at shear rates between 1.15 - 230s -1, it was found that extraction of associated lipids from the glycoprotein lead to 80-85% decrease in the viscosity. Further loss (39%) in viscosity of the delipidated glycoprotein occurred following removal of covalently bound fatty acids. Reassociation of the delipidated glycoprotein with its neutral lipids increased the viscosity 3-fold, a 2.5-fold increase was obtained with glycolipids, and 2-fold with phospholipids. Preincubation of purified mucus glycoprotein with albumin or IgA resulted in the increase in viscosity. This increase in viscosity was proportional to albumin concentration up to 10%, and to IgA concentration up to 5%. The results show that interaction of lipids and proteins with mucus glycoprotein contributes significantly to the viscosity of gastric mucus. | lld:pubmed |
pubmed-article:6732822 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6732822 | pubmed:language | eng | lld:pubmed |
pubmed-article:6732822 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6732822 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:6732822 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6732822 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6732822 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6732822 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6732822 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6732822 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:6732822 | pubmed:month | Jun | lld:pubmed |
pubmed-article:6732822 | pubmed:issn | 0006-291X | lld:pubmed |
pubmed-article:6732822 | pubmed:author | pubmed-author:SlomianyB LBL | lld:pubmed |
pubmed-article:6732822 | pubmed:author | pubmed-author:SlomianyAA | lld:pubmed |
pubmed-article:6732822 | pubmed:author | pubmed-author:SarosiekJJ | lld:pubmed |
pubmed-article:6732822 | pubmed:author | pubmed-author:MurtyV LVL | lld:pubmed |
pubmed-article:6732822 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:6732822 | pubmed:day | 15 | lld:pubmed |
pubmed-article:6732822 | pubmed:volume | 121 | lld:pubmed |
pubmed-article:6732822 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:6732822 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:6732822 | pubmed:pagination | 521-9 | lld:pubmed |
pubmed-article:6732822 | pubmed:dateRevised | 2008-11-21 | lld:pubmed |
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pubmed-article:6732822 | pubmed:year | 1984 | lld:pubmed |
pubmed-article:6732822 | pubmed:articleTitle | Effect of lipids and proteins on the viscosity of gastric mucus glycoprotein. | lld:pubmed |
pubmed-article:6732822 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:6732822 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
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http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:6732822 | lld:pubmed |