Linked Life Data

6711840

Source:http://linkedlifedata.com/resource/pubmed/id/6711840

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1984-4-27
pubmed:abstractText
The morphology and permeability of tight junctions of the three major epithelial constituents of rat parotid gland-acinus, intercalated duct, and striated duct-have been examined ultrastructurally. Acinar and intercalated duct junctions (including those surrounding intercellular canaliculi) averaged two to three sealing strands, whereas striated duct junctions had five to eight sealing strands. When the permeability of the junctional complex was probed by means of a recently devised lead ion tracer technique, acinar junctions were found to be very permeable, intercalated duct junctions were somewhat permeable, and striated duct junctions were essentially impermeable to the tracer. Thus, by both morphological and tracer-permeability criteria, acinar tight junctions appear to be "leaky." These data provide strong evidence that, in rat parotid glands, a potential paracellular secretory pathway exists in the acinar region for the transepithelial passage of fluid.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0003-276X
pubmed:author
pubmed:issnType
Print
pubmed:volume
208
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
69-80
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Freeze-fracture and lead ion tracer evidence for a paracellular fluid secretory pathway in rat parotid glands.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.