Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1984-5-24
pubmed:abstractText
The selective alpha1-adrenergic antagonist prazosin has recently been recommended for the preoperative management of pheochromocytoma, but we have observed a hypertensive crisis in a patient with such a tumor, despite prazosin therapy. Her blood pressure was easily controlled with small doses of phenoxybenzamine, suggesting that less selective alpha-adrenergic blockade might be advantageous in this situation. The involvement of alpha 2-adrenoreceptors in pressor responses and a lack of evidence for presynaptic alpha 2 control of peripheral sympathetic tone in man suggest that selective alpha 1-blockade is not the optimal treatment of hypertension due to high levels of circulating catecholamines.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0038-4348
pubmed:author
pubmed:issnType
Print
pubmed:volume
77
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
535-6
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Hypertensive crisis in prazosin-treated pheochromocytoma.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Case Reports