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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1984-5-24
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pubmed:abstractText |
The selective alpha1-adrenergic antagonist prazosin has recently been recommended for the preoperative management of pheochromocytoma, but we have observed a hypertensive crisis in a patient with such a tumor, despite prazosin therapy. Her blood pressure was easily controlled with small doses of phenoxybenzamine, suggesting that less selective alpha-adrenergic blockade might be advantageous in this situation. The involvement of alpha 2-adrenoreceptors in pressor responses and a lack of evidence for presynaptic alpha 2 control of peripheral sympathetic tone in man suggest that selective alpha 1-blockade is not the optimal treatment of hypertension due to high levels of circulating catecholamines.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0038-4348
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
77
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
535-6
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:6710216-Adrenal Gland Neoplasms,
pubmed-meshheading:6710216-Catecholamines,
pubmed-meshheading:6710216-Female,
pubmed-meshheading:6710216-Humans,
pubmed-meshheading:6710216-Hypertension,
pubmed-meshheading:6710216-Middle Aged,
pubmed-meshheading:6710216-Phenoxybenzamine,
pubmed-meshheading:6710216-Pheochromocytoma,
pubmed-meshheading:6710216-Prazosin,
pubmed-meshheading:6710216-Premedication,
pubmed-meshheading:6710216-Quinazolines
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pubmed:year |
1984
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pubmed:articleTitle |
Hypertensive crisis in prazosin-treated pheochromocytoma.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Case Reports
|