Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1984-3-28
|
pubmed:abstractText |
Fluoresceinated human albumin conjugated with histamine (FHA-HIS) has been used for the demonstration of histamine receptors on human platelets. Such receptors were demonstrated on 40-63% of peripheral blood platelets in 4 healthy donors. The binding of FHA-HIS was inhibited on 35-79% of the platelets by the histamine H1 receptor antagonists diphenhydramine and clemastine. The histamine H2 receptor antagonist cimetidine blocked the FHA-HIS binding on 14-37% of the platelets. It is concluded that histamine H1 as well as H2 receptors occur on human platelets but the receptors are not equally distributed in the platelet population.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Feb
|
pubmed:issn |
0036-553X
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
32
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
113-8
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:6701456-Blood Platelets,
pubmed-meshheading:6701456-Cimetidine,
pubmed-meshheading:6701456-Flow Cytometry,
pubmed-meshheading:6701456-Humans,
pubmed-meshheading:6701456-Receptors, Histamine,
pubmed-meshheading:6701456-Receptors, Histamine H1,
pubmed-meshheading:6701456-Receptors, Histamine H2
|
pubmed:year |
1984
|
pubmed:articleTitle |
Demonstration of histamine receptors on human platelets by flow cytometry.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|