Linked Life Data

6669360

Source:http://linkedlifedata.com/resource/pubmed/id/6669360

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1984-4-6
pubmed:abstractText
The possible multiple effect of galactose diet and X-irradiation on cataract development in mice was investigated by scanning electron microscopy. X-ray cataracts were induced by maintaining animals either on a normal or 50% galactose diet. No detectable changes in lens morphology were seen in animals fed galactose alone compared with normal controls. 2 months after X-ray, less damage had occurred to the lenses of the galactose-fed animals compared to those on a normal diet. At 4 months after X-ray, animals on a normal diet developed mature cataracts, while in the galactose-fed animals they were delayed by 0.5-1.5 months. Suppression of the development of X-ray cataract by galactose feeding may be related to the ability of this sugar, which accumulates in mouse lens due to the low levels of aldose reductase, to act as a free radical scavenger.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0030-3747
pubmed:author
pubmed:issnType
Print
pubmed:volume
15
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
324-33
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Scanning electron microscopy of X-ray-induced cataract in mice on normal and galactose diet.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.