Linked Life Data

6667838

Source:http://linkedlifedata.com/resource/pubmed/id/6667838

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1984-3-29
pubmed:abstractText
Plasma total thyroxine (T4) and testosterone concentrations of Day 15.5 intact, surgically partially decapitated (hypothalamo-hypophyseoprivic) and partially decapitated chick embryos with adenohypophyseal transplants were determined by radioimmunoassay of the same plasma sample. Decapitation in both male and female chick embryos at 33-38 h of incubation results in plasma thyroxine and testosterone levels which are statistically significantly lower than those of intact embryos. The addition of a single adenohypophyseal transplant to the chorioallantoic membrane (CAM) of male and female decapitated embryos only partially restores plasma thyroxine levels to intact levels. However, the same procedure results in plasma testosterone levels which are higher than those of both decapitated and intact individuals. The data suggest that in the developing chick embryo there are differences in dependence of the thyroid and the gonads upon a functional hypothalamo-adenohypophyseal unit. The possible differential regulatory effects of the hypothalamus on the adenohypophyseal-thyroid and adenohypophyseal-gonadal components of the hypothalamic-adenohypophyseal-thyroid and hypothalamic-adenohypophyseal-gonadal axes are discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0016-6480
pubmed:author
pubmed:issnType
Print
pubmed:volume
52
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
357-64
pubmed:dateRevised
2005-11-17
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Hypothalamo-adenohypophyseal-thyroid and gonadal interrelationship in the chick embryo. I. Differential effect of ectopic pituitary grafts on plasma total T4 and testosterone levels.
pubmed:publicationType
Journal Article